You might consider going the route of referb’d hardware… and adding some newer GPUs if desired.
@randy mentioned in the madrona labs forum about getting a new dev box from these folks https://www.theserverstore.com/. I was curious and looked at what they had - they sell HP Z workstations which I can say from first hand experience are built like tanks and stand up to heavy use (animation, rendering, simulation, etc.)
The prices on used Z620 and Z820 are low enough that I’m tempted to get one for home use. My daily driver at work for the last four years has been a Z820 which has never left me wanting more (16 core, 32GB ram, Quadro 4000).