I’m on the fence right now about whether a DC-coupled audio interface is even the right thing for controlling modular (or CV-enabled guitar pedals) from a laptop. This kind of setup is just amazing for lab use though - you can build one heck of an audio-band scrolling storage scope on linux/openGL.
On the other hand a monome-serial-ish CV output could be made hot-pluggable from linux laptop like a grid. You could send pairs of numbers [CV-level, slew-rate] as OSC messages or similar.
The aleph may eventually fill this if CV-DAC driver issues can be surmounted but I think it could also be done with a teensy. Yanking USB soundcard on low-latency jack is a sure recipe for weird hard crashes…