Thanks for the feedback! Very useful! 
Some very good points here! You’ve especially hit the nail on the head with the jack positions.
My initial goal was to have only sound related modules with jacks on the bottom on the top row and control and modulation modules with jacks on the top on the bottom row.
I made this choice both for easy patching (jack positions close to each other) and for making sure the controls are easily accessible. Whilst finding modules with the jacks at the bottom is relatively easy it’s proven a lot harder to find modules with the jacks at the top
so I’ve had to compromise on that initial idea/goal.
I’d still like to work towards this so I’m going to flip my ornament and crime and it I guess it’s kind of inevitable I’ll be making some modules of my own in the future with jacks on top 
Regarding access to important modules like sequencers and mutes: Kria/the grid gives me good access to the main sequencer and easy muting of them as well. The Euclidean circles expansion has mutes as well so I think I’m relatively OK there, although some central mutes might be easier. As you mentioned it’s also about how it feels and works in real life. I’ll just have to try how it works with this combo I guess 
It does seems like a good idea to move the euclidean circles to one of the sides.
Initially I had the drum modules on the top left but that didn’t leave me enough room for the other voices I wanted. I think I’ll just fall back to using a tiptop BD808 or the still to be released erica synths drums2 which should give me enough space to move the drum modules back to the top left, than I can move the euclidean circles + expansion to the bottom left.
I totally recognize this, so thanks for bringing it up! I already use a similar approach, just with twice as many colors
White for audio, black for control/CV. It gives me a slightly easier overview than all the same colors and is still simple/minimal enough to not kill me with all the colors 
Bit of a tangent, but I’m using erica synths cables as well and the last 30cm black ones I got are very stiff and kink easily unlike the older ones I have. How are yours?