You can certainly set this up, and I have with a multisampled piano, one for each note. You have to add a sample player for each voice, I have only done up to four voices as that is my midi to CV limit. I believe someone has implemented round robin as well so you could use a single pitch and gate to trigger multiple voices.
It takes some CPU but for four voices you still have a little headroom for other things. It would most likely take more effort, compared to the disting, to get the patch going initially, but you can make a quicksave or custom unit and get it back.
Regarding multisampling piano in the ER301 here is a good thread