In almost all of my patches I use the Wogglebug’s random CV outputs and a randomizer Ardcore sketch to ‘humanize’ the sound somehow. Even very slight random variations to parameters like envelope length, filter cutoff, etc have a significant psychological effect.
I agree with zebra’s take upthread that it is tempting to just leave this stuff in, but ultimately it makes for less satisfying listening. What I end up doing is recording various parts in takes and choosing the ones where the randomness lines up the most neatly. Alternately, if I hear some random interaction or movement that is particularly pleasing, I’ll try to find a way to engineer that deliberately, and often discover something new along the way.
Ultimately, though, I struggle with chance and randomness, because my personality likes to be in control. Having worked with computers my entire life I have the built in feeling that “undo” is right there, or that “perfect” is attainable (which, in the digital sense, it is). This tendency is a bit of a hindrance to creativity; the part of my mind that wants to put things in order fights with the part that can appreciate the aesthetics of asymmetry and disorder. Right now, the former part is more agile and well-trained than the latter, but with practice the balance seems to be shifting.