i’d say it kinda depends if you want to use the STM HAL, or something else, like the Mutable HAL stack. if the latter, you’re good to go with a Clouds i think. but i dunno how easy it would be to adapt to a raw breakout board like that one.
4ms and whimsical are other companies whose repos you can look at, i think both build on the MI work.
if you want to use STM HAL, it’s probably easiest to get a Discovery board and use the stack of stuff maintained / supported by STM. i recently had a fine experience with stm32f746g-discovery which is pretty cheap (though not $14 cheap!) and has tons of peripherals that are helpful for prototyping. (like, a touchscreen.)
i’ve done two audio projects with STM HAL. a few years ago someone else set it up, last year i started over myself. it was, frankly, a total pain. unfortunately, both projects are proprietary… 
in a nutshell, i managed to build a linux project by using cubemx to figure out some peripheral configuration, openSTM (aka System Workbench, a customized Eclipse) to clone demo projects and get things going, and then translated everything into CMake / Makefiles with the standard arm toolchain / GDB. this was all a huge drag and i would love to see a better way, but at least it’s possible with open source toolchains.
honestly if you are worried about spending time in rabbitholes and just want the quickest path to coding something, that’s probably just getting a discovery board and using the System Workbench stack on windows.
thing is, the HAL abstracts so much stuff that you’re not really dealing with the instruction set or the MCU architecture. that’s probably fine; grokking the HAL and the examples will force you to read plenty of the arch documentation anyways, which is a baseline for rolling your own stack or whatever.
also, @csboling is on the nose with the observation that the stm-specific stuff and the audio stuff are basically completely orthogonal. all the painful crap is about configuring timers, memory, I/O, blabla. the audio stuff can and should be prototyped elsewhere first.