Two excerpts from the manual about unclocked channels:
Using X and Y-CV inputs and their associated attenuator / combo pots with FUN.CV settings:
Set up an unclocked X or Y channel with 4-octave output range on the QUANT page, and current location knob turned all the way counterclockwise, and FUN.CV.ADD or FUN.CV.S&H engaged. This will let you use the channel’s CV input as an ersatz quantizer.
Using unclocked channels in Latch Mode:
When the channel is unclocked and you touch a Location, R2 will go to that Location and output a Gate. Enable a Location and adjust associated Knob to set Location CV value. This is very useful for tuning notes in a melodic pattern. Just select the Location you want to tune, adjust the Location’s knob, then move to the next Location and repeat.
If Z.ON is engaged on the Global Page, you can use the Latch page to interact with René while modulating the Z-Axis. This is a non-destructive way to improvise over pre-programmed states. In other words, as you progress from one state to the next, your latch is maintained. Latch is not stored and does not alter Program Pages in the selected State.
Note: Single-location Latches will cause X or Y channels to output gates at the clock rate, but the Cartesian channel must have two or more locations Latched for the same behavior. This is due to slight differences in the way these channels create gates, and can be used as a quick way to fully stop the Cartesian channel in performance without stopping X or Y Clocks.