I have three W/ that I use daily at this point. They are central to my setup. Started out with one and loved the compositional possibilities with it, so I bought one more at a time when they popped up for good deals in the trade section here. All of my w/ are set to dub.that. I use channel 2 & 3 of maths as my feedback knobs.
My standard patch sounds similar to what @voidstar describes, I’ll run a simple voice or two into one looping W/ (set to generate -5/+5v ramp on this) then out to Cold Mac panning section. Left and right out to different W/s (with different loop lengths), set up as a stereo pair each set to cue.this so I can tempo sync down the line. I’ve got a buff mult and a matrix mixer so I often turn off global monitoring and set up interesting wet/dry mixes on the fly.
I’ve also got a teletype, but I find I mostly use WS.PLAY to turn everything off/on in consistent ways for dramatic effect. I’ve had WS.CUE 0 freeze my teletype a couple of times (though not every time and I still try it every now again.)
I find the w/ physical gestures to be pretty easy to use, but I did have the little card in front of me for the first month. I feel pretty confident flying through the different modes, using cue mode to quickly delete cues, turning monitoring on and off, etc. I do find myself clearing tapes to start fresh more often than I expected. I’m definitely not confident enough to switch this/that modes without instructions handy. I wish that I could play loops in reverse without the serious clicks that happen at cue points. But still, I feel comfortable enough with them in my system to play them live and, while I haven’t yet, it is my big goal this year. I love how I can take simple source material and make it into something expansive.