I’m not totally sure I catch your meaning - are we talking about writing new firmware for the Midifighter in order to make the sequencer more flexible / work differently or are we talking about a script that was Midifighter-aware and was built around the strengths of the Midifighter sequencer implementation?
I suspect you mean the latter, which is a very cool idea. I lack the skill at this time to do something like that but being trapped indoors for the foreseeable future and having a light background in python, who knows!
I was able to snag a b-stock Twister from the nice people at DJ Tech Tools last night, so in a few days I’ll be able to play with the hardware directly and will report back.