I’ve been out of the PT world for awhile now but I dont think you’d run into many issues using something non-avid hardware related as your AD/DA converters on regular PT software. A lot of my friends are using standard PT with a few Apollos on a Mac Mini and are running just fine in their studios.
Maybe i havent looked into Pro Tools HD often but i feel as if new computers are fast enough now in 2020 that it probably isnt useful unless you are working in a film/TV environment. (Maybe?)
I’m not sure if this answers your question or not.
@brndnwilliams you may have some insight on this?