To provide a counter-point, Suzanne Ciani mentioned in an interview I attended that quad is in her rider–she doesn’t perform if the venue can’t accommodate it.
I think you could consider a performance similar to an installation, and as such being deliberate about venues and sound setups would be a valid artistic consideration, IMO
Random aside, I saw an absolutely incredible set Gavin Rayna Russom performed using two giant Ampeg full-stacks (I think? They were on the stage, I may have imagined that’s where the sound was coming from).
I’m playing a show with the shoegaze-y band I play guitar in this weekend (and for the first time with this project, the modular as well). I’ll be running the guitar and a few voices from the modular (that I will be attempting to mix on the fly) all through my AC-30 inspired by that performance. This one’s at a club, so it will be mic’d and ran through their actual system too. To be determined how that turns out. It’s reverbed way out so probably not that discernible of a difference, hah.