For me serialoscd works on Windows 10, but hotplugging is disabled (so all devices needs to be attached prior to launching serialoscd.exe) and it is in debug mode. I’m getting the same output in the console as you:
[!] running in debug mode, hotplugging disabled
serialosc [m40h1230]: connected, server running on port 17714
For me it’s not a big deal to start serialoscd.exe manually (as opposed to have it automatically started / as a daemon of sorts), but I’d like hotplugging so that I don’t have to have all devices plugged in before starting serialoscd.exe.