I have a MOTU UltraLite AVB and am extremely happy with it. It was a bit glitchy in the beginning (got it right when they came out), but they released several firmware updates that fixed those problems and it now runs smoothly on the latest OS X.
Have you looked into the possibilities offered by the AVB standard? You can do some extremely cool stuff with it, like connect multiple computers to a single audio interface and freely route audio between them (up to 128 channels at 44.1/48 kHz with the Thunderbolt AVB devices I think). Or you can route audio internally on your machine with pretty much the same flexibility of tools like Soundflower and Jack. This is especially great since Jack doesn’t seem to work on OS X 10.11 at all and Soundflower is difficult to install.
Oh and the GUI for the MOTU AVB devices is entirely browser-based, so you can control your interface from any device on your local network - iOS, Android, another laptop, you name it
And if you’re ever feeling like you wanna put on a truly huge show, you can link and connect a whole bunch of these and it all runs on regular ethernet cables.
The thing that drew me initially to the UltraLite was that it had so many analog ins and outs on a portable interface (and the Thunderbolt equipped bigger devices have even more, like the 16A). I only found out about all the AVB tricks after I bought it, which was quite a pleasant surprise. Oh and it does have MIDI in and out as well 