I’m not sure I’m understanding correctly, but the first thing to say is that you can comment lines by hand using ALT-/

If you’re wanting to prevent a line from running programmatically, then you can use an IF. For example you could have a variable A, which if it was non-zero would trigger the thing to run and otherwise skip it by using IF A: and then the rest of the line would be your code.

I suspect this isn’t what you’re after, but just in case!