This sounds about right. 16n requires you to flash it to behave how you’d like - its integration with ER-301 requires 16n to be the master, but its integration with TXB/Teletype requires Teletype to be master. If I was thinking sharper I might have done something with pullups, but we have exposed USB and the kind of people who’d want to change that are probably OK with flashing a Teensy.