The built-in Defender software in Windows 10 works well. It automatically updates every day and stays out of the way. I feel no need to run any third party anti-virus software. When I’ve used Kaspersky and others in the past, they continually bothered me with pop-ups trying to upsell me. And they hook so deeply into the OS that they’ve caused problems for some people when upgrading to newer versions of Windows.
I try to practice safe Internet habits. I avoid clicking on potential phishing links in emails, I avoid visiting untrustworthy sites, I keep all software up to date (especially browser and OS), I don’t download executables from unknown sites, etc.