That’s the routing I have. I have another Lipsk I debated putting in between the Drezno and Jena, but no space in a small case really. I actually have a 2nd Drezno. I fried it while I was waiting for the Jena and didn’t want to wait for repairs. I’ll likely sell it when I get it back, but - hey, it’s so cool, maybe I could use a Drezno/Lipsk for sequencing and another for waveshaping! 
Personally, I think the Lipsk is critical, but the more you play with it, it obviously depends on your goals. If you want it as a sequencer, I think it’s well worth it. If you’re using the system for waveshaping, maybe it isn’t worth it unless you really get particular about what kind of grit you want or more choices of subtle grit variations.
Over spring break I spent some time exploring a small case with it in there and recorded quite a few ideas almost every day, so about 45 minutes of stuff, most of which just doesn’t hold up, but I’m trying to sculpt into what may be a 10-12 minute ‘song’, or maybe I’ll trash it all! BUT it was mostly an excuse to just force myself to have the mindset of ‘finishing’ some ideas each day to push a bit of discipline into my work practice that often gets lost in the wack aimless meandering that I think most of us get caught up in with modular.
Mostly I used the system as a sequencer and sending even the most simple LFO into the Drezno can yield really interesting results, but flipping the bits with a Lipsk can really take things to another level. The Jena I’ve only gotten more recently, but I think it adds a lot of potential to the system. I guess my early impressions suggest that it can sort of smooth out the edges of the output quite often - but the percussion waveset and some of the others are interesting too. The clock inputs and outputs are also super important to explore. The only other way I’ve tinkered with it was as a waveshaper, and it’s definitely crazy cool for that, it just isn’t my typical approach and it’s a lot of real estate to ‘just’ do that. I did get a neat overdriven organ kind of sound pushing a Mangrove through I believe.
The system effectively IS a quantizer obviously, but I think if folks are fishing for more musical outputs, a 12 tone scale quantizer might alleviate some frustration if you’re trying to dial in more traditional stuff using this system. I personally am enjoying the kookiness. That said, the more I practice, the more I’ll sort out a closer connection with and control over it. The Jena will take some time because you sort of need to get a feel for the wavetables, which I have trouble wrapping my head around, at least early on.
Otherwise…